Bacground: Hospital acquired infection
(HAI) due to MDA Acinetobacter
baumannii is the great challenge for clinicians in Vietnam as well as in the world.
The results of HAI will lead to prolong the length of hospital stay, increase
cost of treatment and increase case fatality.
Methods: A cross - sectional, descriptive, retrospective study was carried out at department of Tropical
diseases from 1/2012 to 1/2013 on hospitalized patients who discharged with
diagnosis of HAI due to A.baumannii confirmed by positive culture to evaluate the patterns of infection and the
antimicrobial resistances.
Results: 147 specimens with A. baumannii of 132 patients at
the department of Tropical Diseases were isolated in 2012 including 107 samples (73%) of sputum, 29
samples (20%)
of wound
secretions, 8 samples of urines, and 3 samples (2%) of blood cultures. Proven septicemia has low incidence but high case fatality up to 100%.
Isolated strains of A. baumannii are highly resistant to available antimicrobials,
over 80%,
but are still 100% susceptible with
colistin.
Conclusion: HAI due to MDR A. baumannii at the Department of Tropical Diseases is commonly seen with pneumonias, followed with
skin and skin structure infections. The prevention of contamination by apply
and comply the standard precautions of infection control is necessary and
obligatory. Appropriate use of antimicrobials and selection of combination
regimens based on colistin to enhance the efficacy of treatment are very
important.
Key words: Hospital acquired infection (HAI), multi-drug resistant Acinetobacter
baumannii (MDR – A. baumannii), antimicrobial resistances.